Gerald J Atkins Selected Research

drozitumab

9/2017	Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma.
12/2014	Doxorubicin overcomes resistance to drozitumab by antagonizing Inhibitor of Apoptosis Proteins (IAPs).

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Gerald J Atkins Research Topics

Disease

11	Bone Resorption 11/2018 - 08/2008
10	Osteolysis 12/2019 - 10/2006
7	Neoplasms (Cancer) 09/2017 - 06/2002
6	Infections 12/2023 - 01/2018
6	Hypoxia (Hypoxemia) 09/2021 - 10/2014
5	Osteosarcoma (Osteogenic Sarcoma) 09/2017 - 06/2002
4	Tibial Plateau Fractures 11/2022 - 01/2015
4	Inflammation (Inflammations) 01/2017 - 08/2006
3	Bone Fractures (Bone Fracture) 01/2017 - 07/2004
3	Bone Diseases (Bone Disease) 01/2017 - 04/2015
3	Breast Neoplasms (Breast Cancer) 03/2016 - 08/2014
2	Osteomyelitis 08/2022 - 01/2018
2	Secondary Hyperparathyroidism 01/2022 - 11/2016
2	Chronic Renal Insufficiency 01/2022 - 01/2021
2	Hyperphosphatemia 01/2021 - 01/2021
2	Hypercalcemia (Milk Alkali Syndrome) 01/2021 - 08/2008
2	Necrosis 01/2019 - 10/2006
2	Neoplasm Metastasis (Metastasis) 09/2017 - 02/2015
2	Rickets (Rachitis) 11/2016 - 10/2014
2	Bone Neoplasms (Bone Cancer) 09/2015 - 04/2015
2	Bacterial Infections (Bacterial Infection) 04/2015 - 01/2012
2	Osteoporosis 12/2013 - 08/2013
2	Rheumatoid Arthritis 03/2011 - 08/2006
2	Multiple Myeloma 03/2009 - 09/2003
1	Femoral Fractures (Femoral Fracture) 10/2023
1	Hip Osteoarthritis (Coxarthrosis) 01/2023
1	Cognitive Dysfunction 01/2022
1	Iron Deficiencies 09/2021
1	Anemia 01/2021
1	Dementia (Dementias) 01/2021
1	Hypophosphatemia 01/2021

Drug/Important Bio-Agent (IBA)

7	Vitamin D FDA LinkGeneric 01/2018 - 06/2007
7	CalciumIBA 11/2016 - 08/2008
5	Messenger RNA (mRNA)IBA 01/2021 - 09/2003
5	Polyethylene (Polythene)IBA 01/2019 - 10/2006
4	MineralsIBA 01/2021 - 12/2013
4	CytokinesIBA 01/2019 - 06/2002
4	LigandsIBA 08/2014 - 07/2005
3	TH 302IBA 09/2017 - 02/2015
3	ProdrugsIBA 09/2017 - 02/2015
3	Calcitriol Receptors (Calcitriol Receptor)IBA 11/2016 - 07/2013
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2009 - 06/2002
2	Anti-Bacterial Agents (Antibiotics)IBA 12/2023 - 08/2022
2	IronIBA 09/2021 - 01/2021
2	Proteins (Proteins, Gene)FDA Link 09/2021 - 09/2003
2	TitaniumIBA 01/2021 - 01/2012
2	Fibroblast Growth Factor-23IBA 01/2021 - 01/2021
2	hydroxide ionIBA 01/2021 - 07/2013
2	Phosphorus (Red Phosphorus)IBA 01/2021 - 11/2016
2	Hormones (Hormone)IBA 01/2021 - 12/2016
2	MetalsIBA 01/2019 - 10/2006
2	ultra-high molecular weight polyethylene (UHMWPE)IBA 01/2019 - 03/2016
2	DNA (Deoxyribonucleic Acid)IBA 09/2017 - 02/2015
2	drozitumabIBA 09/2017 - 12/2014
2	RANK LigandIBA 01/2017 - 10/2006
2	EnzymesIBA 01/2017 - 07/2013
2	Parathyroid Hormone (Parathormone)IBA 12/2016 - 11/2016
2	25-hydroxyvitamin DIBA 11/2016 - 12/2013
2	Calcitonin Receptors (Calcitonin Receptor)IBA 09/2015 - 08/2008
2	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2015 - 12/2014
2	25-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA 10/2014 - 07/2013
2	OsteoprotegerinIBA 08/2014 - 03/2009
2	Calcitriol (Calcijex)FDA LinkGeneric 08/2008 - 01/2004
2	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 10/2006 - 07/2005
1	ORALIT (ORS)IBA 12/2023
1	Fosfomycin FDA Link 08/2022
1	Fusidic Acid (Fucithalmic)IBA 08/2022
1	LincosamidesIBA 08/2022
1	GlycopeptidesIBA 08/2022
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 08/2022
1	LipopeptidesIBA 08/2022
1	MacrolidesIBA 08/2022
1	FluoroquinolonesIBA 08/2022
1	AminoglycosidesIBA 08/2022
1	TetracyclinesIBA 08/2022
1	StreptograminsIBA 08/2022
1	beta-LactamsIBA 08/2022
1	Cholinergic Antagonists (Anticholinergics)IBA 01/2022
1	Cholecalciferol (Vitamin D3)FDA Link 01/2022
1	Vitamin D3 24-HydroxylaseIBA 01/2022
1	Transferrin Receptors (Transferrin Receptor)IBA 09/2021
1	molidustatIBA 01/2021
1	Chelating AgentsIBA 01/2021
1	Erythropoietin FDA Link 01/2021
1	NitrogenIBA 01/2021
1	Transferrin (beta 2 Transferrin)IBA 01/2021
1	Urea (Carbamide)FDA LinkGeneric 01/2021

Therapy/Procedure

6	Therapeutics 12/2023 - 06/2002
5	Hip Replacement Arthroplasty (Total Hip Replacement) 12/2021 - 12/2013
5	Prostheses and Implants (Prosthesis) 12/2019 - 10/2011
3	Drug Therapy (Chemotherapy) 02/2015 - 06/2002
2	Fracture Fixation 11/2022 - 12/2021
2	Reoperation 12/2021 - 12/2013
2	Cell Transplantation 09/2017 - 03/2009
1	Osteotomy 10/2023
1	External Fixators 10/2023
1	Synchrotrons 01/2023
1	Replantation 12/2021
1	Arthroplasty 12/2021
1	Activities of Daily Living (ADL) 01/2021